Search results for: transgenerational-epigenetics-volume-13

Transgenerational Epigenetics

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Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research. Presents a fully-updated and expanded release addressing transgenerational epigenetics, epigenetic mechanisms of gene regulation, and the role of epigenetics in human longevity and cancer Examines the field from "bench-to-bedside", discussing basic science, disease management, current debates, and next steps in epigenetic research and drug discovery Features chapter contributions from international experts

You are the Placebo

Author : Joe Dispenza
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"Throughout history up until present, many cultures have traditionally experienced the effects of verifiable healings, along with hexes, curses, witchcraft, voodoo, and other mysterious phenomena. These effects-many of which were elicited by unscientificmeans-were brought about by the beliefs and lore of the society. Even today, pharmaceutical companies use double- and triple-blind randomized studies in an attempt to exclude of the power of the mind over the body. In You Are the Placebo, Dr. Joe Dispenza explores the history, the science, and the practical applications of the so-called placebo effect. Citing many amazing individual cases studies, this compelling book will empower you to personally use "the expectation of a particular outcome" to alter your internal states-as well as external reality-solely through the action of your mind. It offers the necessary understandings to change old beliefs and perceptions into new ones. In addition, it teaches a model of personal transformation that correlateswith the placebo effect-without the need for any external influences ("placebos" such as sugar pills, saline injections, and so on). You Are the Placebo combines the latest research in neuroscience, biology, psychology, hypnosis, behavioral conditioning, and quantum physics to demystify the workings of the placebo effect. and show how the seemingly impossible can become possible. "--

Extended Heredity

Author : Russell Bonduriansky
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How genes are not the only basis of heredity—and what this means for evolution, human life, and disease For much of the twentieth century it was assumed that genes alone mediate the transmission of biological information across generations and provide the raw material for natural selection. In Extended Heredity, leading evolutionary biologists Russell Bonduriansky and Troy Day challenge this premise. Drawing on the latest research, they demonstrate that what happens during our lifetimes--and even our grandparents' and great-grandparents' lifetimes—can influence the features of our descendants. On the basis of these discoveries, Bonduriansky and Day develop an extended concept of heredity that upends ideas about how traits can and cannot be transmitted across generations. By examining the history of the gene-centered view in modern biology and reassessing fundamental tenets of evolutionary theory, Bonduriansky and Day show that nongenetic inheritance—involving epigenetic, environmental, behavioral, and cultural factors—could play an important role in evolution. The discovery of nongenetic inheritance therefore has major implications for key questions in evolutionary biology, as well as human health. Extended Heredity reappraises long-held ideas and opens the door to a new understanding of inheritance and evolution.

Environmental Health Perspectives

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Best Practice Research

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New Scientist

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Science

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Proceedings of the National Academy of Sciences of the United States of America

Author : National Academy of Sciences (U.S.)
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Annals of the Academy of Medicine Singapore

Author : Academy of Medicine (Singapore)
File Size : 90.81 MB
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Fitzpatrick s Dermatology Ninth Edition 2 Volume Set EBOOK

Author : Sewon Kang
File Size : 64.36 MB
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The gold-standard text in dermatology – completely updated for today’s practice by an all-new editorial board Encyclopedic in scope, yet skillfully edited to make it easy to read and understand, this trusted classic delivers everything clinicians need to know about skin, skin symptoms, and skin diseases. Presented in full color, Fitzpatrick’s covers all the essentials, from the basic science of skin to the day-to-day clinical issues of managing common skin disorders such as acne, skin cancer, and psoriasis. Backed by the expertise of more than 500 world-renowned contributors, and the reference of choice for clinicians, students, and educators, Fitzpatrick’s is enhanced by thousands of full-color photographs and a wealth of newly enhanced tables and diagrams. The Ninth Edition is bolstered by a new global editorial team; a reorganized table of contents; a more simple, readable, and direct writing style, the incorporation of more genetic, syndromic, and treatment information into each chapter; the addition of first, second, and third line treatment options; and improved table presentation. The reorganized table of contents reflects how disease presents rather than its cause.

Genetics Abstracts

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BMJ

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Crop Science

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Effects of Ionizing Radiation

Author : United Nations. Scientific Committee on the Effects of Atomic Radiation
File Size : 55.8 MB
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The purpose of this annex is to summarize the literature on non-targeted effects associated with exposure to ionizing radiation and, where possible, to evaluate how such effects may affect risks associated with radiation exposure, the understanding of radiation-induced carcinogenesis, and the mechanistic basis for interpreting epidemiological data on radiation effects.

Epigenetics and Human Health

Author : Alexander Haslberger
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After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.

Fanaroff and Martin s Neonatal Perinatal Medicine E Book

Author : Richard J. Martin
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Fanaroff and Martin’s Neonatal-Perinatal Medicine covers everything you need to improve the quality of life and long-term outcomes of your patients. Drs. Richard J. Martin, Avroy A. Fanaroff, and Michele C. Walsh, along with a multi-disciplinary team of contributors guide you through the sweeping developments in diagnosis and treatment of the mother fetus, and neonate. The completely updated 9th edition keeps you current on the late preterm infant, the fetal origins of adult disease, neonatal anemia, genetic disorders, and more. Get comprehensive guidance on treating patients through a dual focus on neonatology and perinatology. See nuances and details in over 800 illustrations that depict disorders in the clinical setting and explain complex information. Find the information you need easily with indexing in both volumes that provides quick access to specific guidance. Spot genetic problems early and advise parents of concerns thanks to completely new section on this topic. Tackle the health problems associated with preterm births through a new chapter on The Late Preterm Infant. Understand the fetal origins of adult disease through a new chapter that focuses on conditions that originate in the womb. Stay current on the developments and research surrounding neonatal anemia from the entirely new chapter on Blood and Hematopoietic System highlights. Obtain more global perspectives and best practices from an increased number of international contributions in this edition.

Epigenetic Regulation in the Nervous System

Author : J. David Sweatt
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Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions. Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia. BMA Medical Book Awards 2014 - Highly Commended, Neurology, British Medical Association BMA Medical Book Awards 2014 - First Prize, Neurology, British Medical Association 2013 PROSE Award winner for Best in Reference Works and Best Single Volume Reference in Science from the Association of American Publishers Presents a unified view of epigenetic mechanisms from behavior to genes and everything in between Discusses clinically relevant disorders in the context of epigenetics research, making the volume appealing to clinicians as well as basic scientists Provides numerous practical examples for the new investigator to facilitate implementation of research in neuroepigenetics

Knobil and Neill s Physiology of Reproduction

Author : Tony M. Plant
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The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context. The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field. Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction. Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.

Respiratory Epidemiology

Author : Isabella Annesi-Maesano
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Over the last decade, the volume of research into the pathophysiology and genetics of pulmonary diseases has increased greatly. This has led to the development of new treatments and therapies for many diseases, including lung cancer, asthma and cystic fibrosis. This issue of the ERS Monograph comprehensively demonstrates the developments in respiratory medicine in recent years. It outlines the importance of epidemiology in respiratory medicine, and will prove a methodological tool that will help disease management. It should also be used as an advocacy tool for the sake of public health.

Encyclopedia of Genetics Genomics Proteomics and Bioinformatics 8 Volume Set

Author : Lynn B. Jorde
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Available in print and online, this unique reference brings together all four fields of genetics, genomics, proteomics, and bioinformatics to meet your dynamic research requirements. It brings together the latest concepts in these vibrant areas and ensures a truly multidisciplinary approach. Topics include genetic variation and evolution, epigenetics, the human genome, expression profiling, proteome families, structural proteomics, gene finding/gene structure, protein function and annotation, and more. The work incorporates a vast amount of topical information, profiles cutting-edge techniques, and presents the very latest findings from an international team of over five hundred contributors. With articles for both students and more experienced scientists, this is a key reference source for everyone. Contains more than 450 articles covering all aspects of genomics, proteomics, bioinformatics and related technologies Includes a glossary containing over 550 clear and concise definitions "I am pleased to recommend it heartily as a essential reference tool…should remain the definitive work…for many years to come." THE CHEMICAL EDUCATOR “Jorde…and co-editors have done a remarkable job in coordinating this information, distilling it into a package that is both easy to navigate and over-flowing in discovery." ELECTRIC REVIEW